Results 121 to 130 of about 217,641 (208)
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou +6 more
wiley +1 more source
Integrative Conservation, EarlyView.After the great Chinese poet Qu Yuan (屈原) was exiled to Xupu (溆浦) county in Hu' nan province, he described the forest there as follows: “mysterious is the deep forest, the place where Yuán yòu dwell (深林杳以冥冥兮,乃猿狖之所居).” What is the referent of the name Yuán yòu in this sentence?
Kefeng Niu
wiley +1 more source
Losing brain networks during death
Interdisciplinary Medicine, EarlyView.Abstract Death represents the end of all living organisms. The pattern of brain activity disappearance following death, however, has not been fully elucidated. Here we investigated brain activity dynamics following cardiac arrest using ultra‐high field 11.7 T magnetic resonance imaging (MRI) in longitudinal approach and multi‐modal analyses. Initially,
Han Li +22 more
wiley +1 more source
Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence
Journal of Biophotonics, EarlyView.ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab +4 more
wiley +1 more source
Functional equivalence and class expansion in rats using olfactory stimuli
Journal of the Experimental Analysis of Behavior, EarlyView.Abstract Simple discrimination reversal procedures have been successful in demonstrating functional equivalence classes in animals. The current study tested whether class expansion could be demonstrated in rats following the formation of functional equivalence classes.
Elijah J. Richardson +4 more
wiley +1 more source
Genetically‐targeted control of the spinal cord and peripheral nervous system
Journal of Intelligent Medicine, EarlyView.Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano +3 more
wiley +1 more source
Magnetic Resonance Acoustic Radiation Force Imaging (MR‐ARFI)
Journal of Magnetic Resonance Imaging, EarlyView.This review covers the theoretical background, pulse sequence considerations, practical implementations, and multitudes of applications of magnetic resonance acoustic radiation force imaging (MR‐ARFI) described to date. MR‐ARFI is an approach to encode tissue displacement caused by the acoustic radiation force of a focused ultrasound field into the ...
Henrik Odéen +2 more
wiley +1 more source