Results 131 to 140 of about 578,331 (406)

Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2005
To further study the role of GPR54 signaling in the onset of primate puberty, we used the monkey to examine the ability of kisspeptin-10 to elicit the release of gonadotropin-releasing hormone (GnRH) precociously, and we describe the expression of GPR54 ...
M. Shahab   +5 more
semanticscholar   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

open access: yesAdvanced Science, EarlyView.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain   +9 more
wiley   +1 more source

Hippocampal damage associated with prolonged glucocorticoid exposure in primates

open access: yesJournal of Neuroscience, 1990
In the laboratory rat and guinea pig, glucocorticoids (GCs), the adrenal steroids that are secreted during stress, can damage the hippocampus and exacerbate the hippocampal damage induced by various neurological insults.
R. Sapolsky, H. Uno, C. Rebert, C. Finch
semanticscholar   +1 more source

Core promoter short tandem repeats as evolutionary switch codes for primate speciation [PDF]

open access: yes, 2015
Alteration in gene expression levels underlies many of the phenotypic differences across species. Because of their highly mutable nature, proximity to the +1 transcription start site (TSS), and the emerging evidence of functional impact on gene ...
Bagheri, A.   +8 more
core  

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

open access: yesAdvanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong   +16 more
wiley   +1 more source

Monitoring cardiovascular function in the primate under prolonged weightlessness [PDF]

open access: yes
Monitoring cardiovascular function in primates under prolonged ...
Meehan, J. P., Rader, R. D.
core   +1 more source

Efficient Somatic Cell Nuclear Transfer by Overcoming Both Pre‐ and Post‐Implantation Epigenetic Barriers

open access: yesAdvanced Science, EarlyView.
Mammalian cloning via SCNT is limited by several epigenetic barriers. Kdm4d/Kdm5b overexpression plus TSA treatment overcomes epigenetic barriers during pre‐implantation development, while tetraploid complementation replaces defective extraembryonic lineages to bypass H3K27me3 imprinting loss to overcome epigenetic barriers in post‐implantation ...
Yamei Li   +13 more
wiley   +1 more source

Dietary Adaptations and Intra- and Interspecific Variation in Dental Occlusal Shape in Hominin and Non-hominin Primates [PDF]

open access: yes, 2016
Dental morphology and tooth shape have been used to recreate the dietary adaptations for extinct species, and thus dental variation can provide information on the relationship between fossil species and their paleoenvironments.
O\u27Neill, Kelsey
core   +1 more source

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