Results 151 to 160 of about 209,233 (218)

Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis

Animal Research and One Health, EarlyView.
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong, Ning Liu, Weining Kong, Xiang Gao, Feifei Guan, Shan Gao, Yuanwu Ma   +6 more
wiley   +1 more source

When the local meets the global: models and challenges of primate conservation in the Fazao-Malfakassa National Park, Togo. [PDF]

Zookeys
Liyabin N, Fousseni F, Aniko PA, Mukete B, Bohnett E, Djagoun C, Gabriel SH, Kperkouma W, Batawila K.   +8 more
europepmc   +1 more source

Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao, Yash Pershad, J. Brett Heimlich, Michelle Ormseth, C. Michael Stein, Brian Sharber, Caitlyn Vlasschaert, Alexander G. Bick, Robert W. Corty   +8 more
wiley   +1 more source

Yellow fever epizootics among non-human primates in Huila, Colombia, 2025-2026. [PDF]

New Microbes New Infect
Sanchez-Rojas IC, Bonilla-Aldana DK, Solarte-Jimenez CL, Bonilla-Aldana JL, Suárez E, Montealegre JL, Suárez M, Rodriguez-Morales AJ.   +7 more
europepmc   +1 more source

Prediction of Human Serum Concentration–Time Profiles of Golimumab and Ustekinumab Using Pharmacokinetic Data From Common Marmosets With Assessment of Anti‐Drug Antibodies

Biopharmaceutics &Drug Disposition, EarlyView.
This study identified new optimal allometric scaling exponents for human PK prediction of monoclonal antibodies with linear PKs from marmoset PK data. In addition, immunogenicity in common marmosets was evaluated following the repeated dose of golimumab and ustekinumab, minimal anti‐drug antibodies were detected.
Ayaka Tajiri, Shogo Matsumoto, Nanami Furukawa, Kensuke Kagiyama, Hiroshi Ikeda, Kazumasa Fukasawa, Hiroki Takano   +6 more
wiley   +1 more source

Anatomical Description of the Main Gyri and Sulci of the Telencephalon of Alouatta belzebul. [PDF]

Anat Histol Embryol
Pereira DKS, de Melo FR, de Melo FCSA, Pereira KF, Vulcani VAS.   +4 more
europepmc   +1 more source

Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Interspecies cross‐reactive protein therapeutics that target conserved epitopes across species are critical for translational research. The present study showcases the engineering of an affibody molecule, originally discovered for binding to human death receptor 5 (hDR5) with 94 nM affinity, to simultaneously acquire cross‐reactivity to murine
Tse‐Han Kuo, Nagamani Vunnam, Jonathan N. Sachs, Benjamin J. Hackel   +3 more
wiley   +1 more source

Hepatitis B Virus in Gabonese Non-Human Primate: Potential Zoonotic Circulation and Long-Term Strain Persistence. [PDF]

Pathogens
Koumba Mavoungou DS, Boundenga L, Lekana-Douki SE, Pendy NML, Moukouama SEK, Kombila LB, Falque G, Mangombi JB, Mouinga-Ondeme A, Dedkov V, Dacheux L, Aghokeng AF, N'dilimabaka N.   +12 more
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Complex Substrates and Bedding for Environmental Enhancement and Research: Or, the Nature of Primates. [PDF]

Am J Primatol
Sayers K, Allen J, Bellanca RU, Brown T, Coleman K, Janavaris M, Khuu JH, Lee GH, Perlman JE, Pomerantz O, Rosga M.   +10 more
europepmc   +1 more source