Results 161 to 170 of about 578,331 (406)
Long‐term immunosuppression of rabbits through oral tacrolimus administration
Oral gavage of rabbits with 1.5 mg/kg/d of tacrolimus allows for an efficient long‐term (1 year) immunosuppression with minimal side effects and no loss of animals. lmmunosuppressed rabbits are a convenient animal model to investigate the long‐term efficacy of human allografts in vivo.
Alexane Thibodeau+4 more
wiley +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica+6 more
wiley +1 more source
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica+4 more
wiley +1 more source
Comparative studies of retinol transport in plasma
The comparative immunology and biochemistry of plasma retinol transport were studied using radioimmunoassays previously developed for human and for rat retinol-binding protein (RBP).
Yasutoshi Muto+2 more
doaj
RESUMO Testamos o efeito de um aparato que pudesse induzir o uso de ferramentas no comportamento de seis macacos-prego cativos. Utilizamos “animal focal” para o tempo gasto em estados comportamentais gerais e estados indicativos de estresse ...
Murilo Reis Camargo+1 more
doaj +1 more source
We generated two neuron‐specific Cre rat lines, Thy1‐Cre and NeuN‐Cre, using CRISPR/Cas9‐mediated targeted insertion. Both lines were validated for high neural specificity by crossing them with a Cre reporter rat. When bred with an ND1 conditional knockout rat, the two Cre lines produced distinct phenotypic outcomes. These rat lines have been deposited
Keru Li+15 more
wiley +1 more source
Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates. [PDF]
Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here, we found that 26% of nonhuman primates infected with Asian/American ZIKV in early gestation experienced fetal demise later in pregnancy despite showing few ...
Aagaard, Kjersti M+37 more
core
Research advances in dysphagia animal models
This review systematically summarizes the establishment, evaluation, and detection of dysphagia animal models in stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) in three kinds of experimental animals (including rodents, nonhuman primates, and other mammals), providing a basis for the selection of appropriate animal models of ...
Junhui Bai+5 more
wiley +1 more source