Results 161 to 170 of about 492,641 (339)

Trans-synaptic retrograde degeneration in the visual system of primates [PDF]

, 1963
John M. Van Buren
openalex   +1 more source

Continuous electrocardiogram monitoring in porcine model of myocardial ischemia reperfusion

Animal Models and Experimental Medicine, EarlyView.
Wearable technology for continuous electrocardiogram monitoring can be utilized in porcine models of disease. Abstract As cardiovascular disease is the leading cause of global mortality, innovative animal models are vital to demonstrating the translational value of experimental discoveries. Investigations focused on myocardial remodeling after ischemia
Nathaniel Hyams, Roxanne Swagel, Sharon Thomas, Rupak Mukherjee, Alicia Braxton Hickman, Daniel Eldridge, Kristine Helke, Ying Mei, Jean Marie Ruddy   +8 more
wiley   +1 more source

Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset and short duration of effects in humans

, 2008
Jacob M. Hooker, Youwen Xu, Wynne K. Schiffer, Colleen Shea, Pauline Carter, Joanna S. Fowler   +5 more
openalex   +2 more sources

Menopause in Nonhuman Primates?1 [PDF]

, 2008
Margaret L. Walker, James G. Herndon
openalex   +1 more source

Rapid selection of P323L in the SARS-CoV-2 polymerase (NSP12) in humans and non-human primate models and confers a large plaque phenotype [PDF]

, 2021
Xiaofeng Dong, Hannah Goldswain, Rebekah Penrice-Randal, Ghada T. Shawli, Tessa Prince, Maia Kavanagh Williamson, Nadine Randle, Benjamin Jones, Francisco J. Salguero, Julia A. Tree, Yper Hall, Catherine Hartley, Maximilian Erdmann, James Bazire, Tuksin Jearanaiwitayakul, Malcolm G. Semple, Peter Openshaw, J. Kenneth Baille, Stevan R. Emmett, Paul Digard, David A. Matthews, Lance Turtle, Alistair C. Darby, Andrew D. Davidson, Miles W. Carroll, Julian A. Hiscox, Julian A. Hiscox   +26 more
openalex   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Primate-specific microRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling [PDF]

, 2010
Jin-fang Zhang, Ming‐Liang He, Wei-ming Fu, Hua Wang, Lian-zhou Chen, Xiao Zhu, Ying Chen, Dan Xie, Paul B.S. Lai, Gong Chen, Gang Lü, Marie C. Lin, Hsiang‐Fu Kung   +12 more
openalex   +1 more source

Can nonhuman primate signals be arbitrarily meaningful like human words? An affective approach [PDF]

, 2020
Christine Sievers, Thibaud Gruber
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Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Optimization and Dose Estimation of Aerosol Delivery to Non-Human Primates

, 2015
Ronan MacLoughlin, Geert van Amerongen, James B. Fink, Hettie M. Janssens, W. Paul Duprex, Rik L. de Swart   +5 more
openalex   +2 more sources