Results 61 to 70 of about 205,750 (245)

Erythrocytes of the Rhesus and Cynomolgus Monkeys

open access: yesEuropean Journal of Histochemistry, 2019
The monograph Erythrocytes of the Rhesus and Cynomolgus Monkeys is devoted to the cytologic, quantitative, generative normal and abnormal presentations of the erythrocytes in these two species of primates...
Vincenzo Stingo
doaj   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

open access: yesAdvanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

open access: yesAdvanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi   +12 more
wiley   +1 more source

Vocal communication of White-footed Tamarin (Saguinus leucopus) in the wild

open access: yesCaldasia, 2013
The white-footed tamarin, Saguinus leucopus, is an endemic primate of Colombia whose vocal communication has been little studied. For a period of a month we applied behavior sampling with continuous record, recording tamarins’ vocalizations, and the ...
Fuentes Jesualdo Arturo   +2 more
doaj  

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

open access: yesAdvanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen   +11 more
wiley   +1 more source

CUALIDADES DULCE-ACIDA”: SEÑALES UTILIZADAS POR Ateles fusciceps rufiventris PARA LA ACEPTACIÓN DE LAS FRUTAS

open access: yesActa Biológica Colombiana
La dieta de los monos araña (Ateles spp.) está compuesta en un 90% por frutos maduros. Los monos araña podrían utilizar las cualidades dulce-ácida de las especies de frutos para evaluarlos y aceptarlos por medio del uso del sentido del gusto.
Karol M Gutiérrez Pineda
doaj  

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

open access: yesAdvanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source

Learnable Diffusion Framework for Mouse V1 Neural Decoding

open access: yesAdvanced Science, EarlyView.
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng   +2 more
wiley   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

open access: yesAdvanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang   +21 more
wiley   +1 more source

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