Results 71 to 80 of about 578,331 (406)
Animal Behavior and Cognition, 2021 Humans and nonhuman great apes share a sense for intuitive statistics, making intuitive probability judgments based on proportional information. This ability is of tremendous importance, in particular for predicting the outcome of events using prior ...
Johanna Eckert +4 more
doaj +1 more source
Nonhuman primates as models of hemispheric specialization [PDF]
, 1999 The present chapter concerns the issue of hemispheric specialization for perceptual and cognitive processes. In spite of a long-lasting view that only humans are lateralized (e.g., Warren, 1980), there is now strong documentation for anatomical ...
Dépy, D, Fagot, J, Vauclair, J
core
BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates [PDF]
, 2019 © 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Background: The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have
Cami-Kobeci, Gerta +9 more
core +4 more sources
Advanced Healthcare Materials, EarlyView.This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam +7 more
wiley +1 more source
Primate modularity and evolution: first anatomical network analysis of primate head and neck musculoskeletal system [PDF]
, 2018 Network theory is increasingly being used to study morphological modularity and integration. Anatomical network analysis (AnNA) is a framework for quantitatively characterizing the topological organization of anatomical structures and providing an ...
A Goswami +46 more
core +2 more sources
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
Advanced Healthcare Materials, EarlyView.This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla +16 more
wiley +1 more source
Tool skill impacts the archaeological evidence across technological primates
Scientific ReportsThe archaeological record offers insights into our evolutionary past by revealing ancient behaviour through stone and fossil remains. Percussive foraging is suggested to be particularly relevant for the emergence of tool-use in our lineage, yet early ...
Lydia V. Luncz +8 more
doaj +1 more source
TecnocienciaEn Panamá, las poblaciones del mono tití panameño (Saguinus geoffroyi) se encuentran Casi Amenazadas y a partir del 2015 se prevé una reducción poblacional del 25%.
Karol M. Gutiérrez-Pineda +3 more
doaj +1 more source
Frontiers in Neural Circuits, 2022 Removal of the monosynaptic corticospinal pathway (CSP) terminating within the forelimb segments severely impairs manual dexterity. Functional recovery from the monosynaptic CSP lesion can be achieved through the remaining multisynaptic CSP toward the ...
Taihei Ninomiya +17 more
doaj +1 more source
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advanced Healthcare Materials, EarlyView.Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja +6 more
wiley +1 more source