Results 101 to 110 of about 1,271,098 (314)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Molecules, 2018 The epidermal growth factor receptors (EGFRs), in which overexpression (known as upregulation) or overactivity have been associated with a number of cancers, has become an attractive molecular target for the treatment of selective cancers. We report here
Jia Ke +8 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Square-difference factor absorbing submodules of modules over commutative rings
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria MatematicaLet R be a commutative ring with identity and M an unitary R-module. Recently, in [5], Anderson, Badawi and Coykendalla defined a proper ideal I of R to be a square-difference factor absorbing ideal (sdf-absorbing ideal) of R if whenever a2 − b2 ∈ I for ...
Khashan Hani A., Celikel Ece Yetkin
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Person-Oriented and Subject-Specific Methodology: Some Additional Remarks
Journal for Person-Oriented Research, 2016 Objections that dynamic factor analysis, a prime subject-specific variable-oriented method, enables testing of all central person-oriented theoretical principles are answered in principled ways and a conjecture is presented regarding the relation between
Peter C.M. Molenaar
doaj +1 more source
A report on primes of the form 𝑘⋅2ⁿ+1 and on factors of Fermat numbers [PDF]
, 1958 Raphael M. Robinson
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On the number of prime factors of values of the sum-of-proper-divisors\n function [PDF]
, 2014 Lee Troupe
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FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source