Results 141 to 150 of about 1,271,098 (314)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
STRATEGI BERSAING BIRO PERJALANAN WISATA ALINDO DEWATA TOURS BALI
Jurnal Master Pariwisata, 2015 Alindo Dewata Tours Bali as an inbound tours companydeals with the competitors by applying competitive strategy.Nevertheless the competitive strategy applied is not maximumyet.
Nelsye Natalina Lintong
doaj
TGF-β trap of AdAPT-001 turns up the heat on tumors and turns down checkpoint blocker resistance
Journal for ImmunoTherapy of CancerAt the ASCO 2024 meeting, Anthony P Conley, coauthor on this editorial, presented promising data from the phase 1/2 clinical trial called BETA PRIME (ClinicalTrials.gov NCT04673942) with AdAPT-001 plus a checkpoint inhibitor (CI).
Anthony Conley +4 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
New Evidence for a Flux-independent Spectral Index of Sgr A* in the Near-infrared
The Astrophysical JournalIn this work, we measure the spectral index of Sagittarius A* (Sgr A*) between the H (1.6 μ m) and $K^{\prime} $ (2.2 μ m) broadband filters in the near-infrared (NIR), sampling over a factor ∼40 in brightness, the largest range probed to date by a ...
Hadrien Paugnat +13 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Prime factorizations of finite groups. II
Advances in Group Theory and ApplicationsSummary: This is the second part of our three consecutive papers which develop a theory of prime factorizations of groups. In this part, we show core results. Notably, we completely determine finite \textit{unique factorization groups} (UFGs), i.e. groups with unique prime factorizations (up to equivalence).
openaire +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
ALGEBRAIC ENTROPIES OF NATURAL NUMBERS WITH ONE OR TWO PRIME FACTORS [PDF]
, 2016 Seungpil Jeong +2 more
openalex +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source