Results 201 to 210 of about 216,097 (247)

Investigating and correcting a rare pathogenic mutation in GDF11. [PDF]

HGG Adv
Congdon ST, Bennett J, Opinya R, Agosto AR, Dossias O, Kokko C, Levesque AA, Koob AO, Silver AC, Thomas-Charles CA.   +9 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Inactivated Avian Infectious Bronchitis Virus Strains M41 and 4-91 Provide Broad Protection Against Multiple Avian Infectious Bronchitis Strains. [PDF]

Vaccines (Basel)
van de Weem NMP, Walczak M, van Rooij L, Hormes FAJ, Hesseling P, Timmers L, Wouters PAWM, Raue R.   +7 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Associative and categorical priming in a word-picture paradigm: a diffusion model analysis. [PDF]

Psychol Res
Gao S, Marberg I, Berger A, Voss A.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Spatial artifact detection improves the reproducibility of drug screening experiments. [PDF]

iScience
Ianevski A, Nader K, Potdar S, Gorbonos A, Ianevski F, Tanoli Z, Saarela J, Aittokallio T.   +7 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Association of Preoperative Leukocyte-to-Albumin Ratio with Short- and Long-Term Outcomes After Valvular Heart Surgery: A Retrospective Cohort Study. [PDF]

J Inflamm Res
Lin Y, Liao X, Li S, Yan X, Chen L, Lin Y.   +5 more
europepmc   +1 more source