Results 61 to 70 of about 1,036,687 (287)
Effective Conversion of Non-Prime Graphs to Prime Graphs
International Journal of Analysis and ApplicationsA graph G is considered to have a prime labeling when each of its n vertices is assigned a unique label from the set {1, 2, 3, 4, ..., n}, ensuring that the labels of any two connected vertices are coprime. In the literature, many graph classes identified as prime graphs and non-prime graphs.
Karnam Gurunadhan Tharunraj +1 more
openaire +1 more source
Coprime and prime labelings of graphs
J. Integer Seq., 2016 14 pages, this version is the one accepted by the Journal of Integer ...
Adam H. Berliner +5 more
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
On nonsolvable groups whose prime degree graphs have four vertices and one triangle [PDF]
International Journal of Group Theory, 2018 Let $G$ be a finite group. The prime degree graph of $G$, denoted by $Delta(G)$, is an undirected graph whose vertex set is $rho(G)$ and there is an edge between two distinct primes $p$ and $q$ if and only if $pq$ divides some irreducible ...
Roghayeh Hafezieh
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Some Prime Labeling Results of H-Class Graphs [PDF]
, 2013 Prime labeling originated with Entringer and was introduced by Tout, Dabboucy and Howalla. A Graph G(V,E) is said to have a prime labeling if its vertices are labeled with distinct integers 1, 2, 3, · · · , |V (G)| such that for each edge xy the labels ...
A.Nagarajan +3 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Relative Prime Coprime Graph of Integers Modulo Group and Its Reverse Topological Indices
Pan-American Journal of MathematicsThe relationship between edges and vertices is fundamental to graph theory, significantly influencing different graph properties and applications.
Abdurahim - +3 more
doaj +1 more source