Results 101 to 110 of about 1,529,529 (310)
A formulation of a (q+1,8)-cage
, 2015 Let $q\ge 2$ be a prime power. In this note we present a formulation for obtaining the known $(q+1,8)$-cages which has allowed us to construct small $(k,g)$--graphs for $k=q-1, q$ and $g=7,8$.
Abreu, M. +3 more
core
Prime Graph and Its Structures
, 2023 This was an undergraduate research paper and Dr. Ernest Croot, who is listed as one of the authors of this paper was not notified beforehand and this paper was uploaded without him knowing.
Croot, Ernest, Jin, Patrick
openaire +2 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Some New Results on Prime Graphs
, 2012 We investigate prime labeling for some graphs resulted by identifying any two vertices of some graphs. We also introduce the concept of strongly prime graph and prove that the graphs Cn, Pn, and K1,n are strongly prime graphs.
S. Vaidya, U. M. Prajapati
semanticscholar +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
, 2019 We study the number of connected graphs with $n$ vertices that cannot be written as the cartesian product of two graphs with fewer vertices. We give an upper bound which implies that for large $n$ almost all graphs are both connected and cartesian prime.
Aldi, Marco
core
On minimal prime extensions of a four-vertex graph in a prime graph
Discrete Mathematics, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Brandstädt, Andreas +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source