Results 81 to 90 of about 912,801 (279)
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Consecutive Prime and Highly Total Prime Labeling in Graphs [PDF]
, 2020 This paper examines the graph-theoretical concepts of consecutive prime labeling and highly total prime labeling. These are variations on prime labeling, introduced by Tout, Dabboucy, and Howalla in 1982.
Scholle, Robert
core +1 more source
The prime ideals intersection graph of a ring [PDF]
Commentationes Mathematicae Universitatis Carolinae, 2017 Summary: Let \(R\) be a commutative ring with unity and \(U(R)\) be the set of unit elements of \(R\). In this paper, we introduce and investigate some properties of a new kind of graph on the ring \(R\), namely, the prime ideals intersection graph of \(R\), denoted by \(G_{p}(R)\).
Nikmehr, M. J., Soleymanzadeh, B.
openaire +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Orbit polynomial graphs of prime order
, 1987 We begin with a discussion of orbit polynomial graphs and their relationship with distance-transitive, distance-regular and distance polynomial graphs. After finding a simple classification of the orbit polynomial graphs with a prime number of vertices ...
Beezer, Robert A
core +1 more source
On prime inductive classes of graphs
European Journal of Combinatorics, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
PLoS ONEFor the construction of a common prime divisor graph, we consider an integer [Formula: see text] with its prime factorization, where [Formula: see text] are distinct primes and [Formula: see text] are fixed positive integers. Every divisor of the integer
Ali N A Koam +3 more
doaj +1 more source