Results 71 to 80 of about 33,385 (288)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Forbidden subgraphs of Co-prime graphs of finite groups [PDF]

open access: yesTransactions on Combinatorics
For a finite group $G$ the co-prime graph $\Gamma(G)$ is defined as a graph with vertex set $G$ in which two distinct vertices $x$ and $y$ are adjacent if and only if $gcd(o(x),o(y))=1$ where $o(x)$ and $o(y)$ denote the orders of the elements $x$ and $y$
Swathi V V, M. S. Sunitha
doaj   +1 more source

Capturing Polynomial Time using Modular Decomposition [PDF]

open access: yesLogical Methods in Computer Science, 2019
The question of whether there is a logic that captures polynomial time is one of the main open problems in descriptive complexity theory and database theory.
Berit Grußien
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

On certain prime cordial families of graphs

open access: yesJournal of Taibah University for Science, 2020
Graph labelling is an important tool in modelling real life problems. In the present paper, different graph families are studied for prime cordial labelling.
Nazeran Idrees   +3 more
doaj   +1 more source

Tiling of Prime and Composite Kirchhoff Graphs

open access: yes, 2022
A Kirchhoff graph is a vector graph with orthogonal cycles and vertex cuts. We present an algorithm that constructs all the Kirchhoff graphs up to a fixed edge multiplicity. We explore the tiling of prime Kirchhoff graphs.
Wang, Jessica
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Regular embeddings of complete bipartite maps: classification and enumeration

open access: yes
The regular embeddings of complete bipartite graphs Kn, n in orientable surfaces are classified and enumerated, and their automorphism groups and combinatorial properties are determined.
Jones, Gareth
core   +1 more source

Consecutive Prime and Highly Total Prime Labeling in Graphs

open access: yes, 2020
This paper examines the graph-theoretical concepts of consecutive prime labeling and highly total prime labeling. These are variations on prime labeling, introduced by Tout, Dabboucy, and Howalla in 1982.
Scholle, Robert
core  

Limiting behaviour of random spatial graphs and asymptotically homogeneous RWRE [PDF]

open access: yes, 2005
We consider several random spatial graphs of the nearest-neighbour type, including the k- nearest neighbours graph, the on-line nearest-neighbour graph, and the minimal directed spanning tree.
Wade, Andrew R   +2 more
core  

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