Results 121 to 130 of about 1,529,529 (310)

Prime Labeling of Jahangir Graphs

International Journal of Engineering & Technology, 2018
The paper investigates prime labeling of Jahangir graph Jn,m   for n ≥ 2, m ≥ 3 provided that nm is even. We discuss prime labeling of some graph operations viz. Fusion, Switching and Duplication to prove that the Fusion of two vertices v1 and vk where k is odd in a Jahangir graph Jn,m results to prime graph provided that the product nm is even ...
Anantha Lakshmi., Jayalakshmi. K, Madhavi T   +2 more
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Maximum Edge-Colorings Of Graphs

Discussiones Mathematicae Graph Theory, 2016
An r-maximum k-edge-coloring of G is a k-edge-coloring of G having a property that for every vertex v of degree dG(v) = d, d ≥ r, the maximum color, that is present at vertex v, occurs at v exactly r times. The r-maximum index χr′(G)$\chi _r^\prime (G)$
Jendrol’ Stanislav, Vrbjarová Michaela   +1 more
doaj   +1 more source

Almost-Ramanujan graphs and prime gaps

European Journal of Combinatorics, 2015
The method of Murty and Cioab shows how one can use results about gaps between primes to construct families of almost-Ramanujan graphs. In this paper we give a simpler construction which avoids the search for perfect matchings and thus eliminates the need for computation.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Cubic semisymmetric graphs of order $ 40p $ [PDF]

ریاضی و جامعه
A simple graph $\Gamma$ is called semisymmetric if it is regular and edge-transitive but not vertex-transitive. A simple graph $\Gamma$ is called cubic whenever it is $ 3 $-regular.
Mohammad Reza Salarian, Javanshir Rezaei   +1 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Prime Graphs with Almost True Twin Vertices

Mathematics
A graph G consists of a possibly infinite set V(G) of vertices with a collection E(G) of unordered pairs of distinct vertices, called the set of edges of G. Such a graph is denoted by (V(G),E(G)).
Aymen Ben Amira, Moncef Bouaziz
doaj   +1 more source