Results 31 to 40 of about 641,798 (254)
Gaussian Neighborhood-prime Labeling of Graphs Containing Hamiltonian Cycle [PDF]
, 2019 In this paper, we examine Gaussian neighborhood-prime labeling of generalized Peterson graph and graphs which contain Hamiltonian ...
S T Trivedi, N P Shrimali
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
multicrispr: gRNA design for prime editing and parallel targeting of thousands of targets
Life Science Alliance, 2020 A bioinformatics R package for a fast and generic guideRNA design, optimized for large-scale perturbation assays. Targeting the coding genome to introduce nucleotide deletions/insertions via the CRISPR/Cas9 technology has become a standard procedure.
Aditya M Bhagwat +8 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Momentousness of denture labeling using Aadhaar number in Indian population
Journal of Family Medicine and Primary Care, 2019 Personal identification is of prime importance for forensic and medicolegal purposes especially in case of natural calamities, accidents, state of unconsciousness, or loss of memory. The denture labeling is an important method which has been acknowledged
Neha Sikka +3 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
PRIME LABELING IN DUPLICATE GRAPH OF SOME GRAPHS
, 2019 <p>A graph with vertices is said to admit prime labeling if its vertices can be labeled with distinct positive integers not exceeding such that the labels of each pair of adjacent vertices are relatively prime.
P. Kavitha*1 & A. Rajasekaran2
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source