Results 51 to 60 of about 38,200 (260)

High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics. [PDF]

PLoS ONE, 2015
The importance of single-cell level data is increasingly appreciated, and significant advances in this direction have been made in recent years. Common to these technologies is the need to physically segregate individual cells into containers, such as ...
Assaf Rotem, Oren Ram, Noam Shoresh, Ralph A Sperling, Michael Schnall-Levin, Huidan Zhang, Anindita Basu, Bradley E Bernstein, David A Weitz   +8 more
doaj   +1 more source

Prime Labeling of Jahangir Graphs

International Journal of Engineering & Technology, 2018
The paper investigates prime labeling of Jahangir graph Jn,m   for n ≥ 2, m ≥ 3 provided that nm is even. We discuss prime labeling of some graph operations viz. Fusion, Switching and Duplication to prove that the Fusion of two vertices v1 and vk where k is odd in a Jahangir graph Jn,m results to prime graph provided that the product nm is even ...
Anantha Lakshmi., Jayalakshmi. K, Madhavi T   +2 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Protein labeling approaching its PRIME [PDF]

Nature Methods, 2010
To site-specifically label proteins in living cells, researchers mutate an enzyme to recognize a small fluorophore and catalyze its attachment to a small peptide tag.
openaire   +2 more sources

Prime Labeling of Nauru Graph

International Journal For Multidisciplinary Research, 2023
A graph G = (V(G), E(G)) is observed to admit prime labeling, if a graph that receives prime labeling is called prime graph .In this research article we investigate that the Nauru graph admits prime labeling. We construct the mirror graph and shadow graph of the Nauru graph.
K.Bharatha Devi -, S.Lakshminarayanan -
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Comparative Study of Antimagic Labeling Approaches in Wireless, Interconnection, and Smart Grid Networks

Journal of Mathematics
The antimagic labeling of a graph is an important factor of graph theory, which implies the assignment of individual integer values to the graph’s vertices such that all the vertex sums remain unique. Due to the distinctive feature of antimagic labeling,
Poovarasi P, Kavitha K
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source