Results 71 to 80 of about 641,798 (254)
Extending Undirected Graph Techniques to Directed Graphs via Category Theory
MathematicsWe use Category Theory to construct a ‘bridge’ relating directed graphs with undirected graphs, such that the notion of direction is preserved. Specifically, we provide an isomorphism between the category of simple directed graphs and a category we call ‘
Sebastian Pardo-Guerra +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
On the Graph Isomorphism Completeness of Directed and Multidirected Graphs
MathematicsThe category of directed graphs is isomorphic to a particular category whose objects are labeled undirected bipartite graphs and whose morphisms are undirected graph morphisms that respect the labeling. Based on this isomorphism, we begin by showing that
Sebastian Pardo-Guerra +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
On Prime labeling of some classes of graphs
, 2012 Graph labeling is an important area of research in Graph theory. There are many kinds of graph labeling such as Graceful labeling, Magic labeling, Prime labeling, and other different labeling techniques.In this paper the Prime labeling of certain classes
N. Ramya, K. Rangarajan, R. Sattanathan
core
, 2017 We show that some special families of graphs have prime cordial labeling. We prove that If G is not a prime cordial graph of order m then G∪K_(1,n)is a prime cordial graph if E(G)= n-1,n or n+1 , and we prove that S^' (K_(2,n)), Jelly fish graph , Jewel
M. A. Seoud +2 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Oblong Mean Prime Labeling of Some Snake Graphs [PDF]
, 2017 A graph labeling is an assignment of integers to the vertices or edges or both subject to certain conditions. The graph for which every edge(uv),the labels assigned to u and v are oblong numbers and for each vertex of degree at least 2, the g c d of the ...
, Sunoj B S, Mathew Varkey T K
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Jurnal SisfokomThe adaptation of video games into films or television series has increasingly become a prominent trend in the entertainment sector, often eliciting diverse reactions from audiences.
Danita Divka Sajmira +2 more
doaj +1 more source