Results 91 to 100 of about 641,798 (254)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Super Fibonacci Graceful Labeling [PDF]

open access: yes, 2011
Approaching topics such as Smarandache-Fibonacci triple, graceful labeling, Fibonacci graceful labeling, super Smarandache-Fibonacci graceful graph, super Fibonacci graceful ...
Sridevi, R.   +2 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The economics of GM food labels: An evaluation of mandatory labeling proposals in India [PDF]

open access: yes
"Labeling of genetically modified (GM) foods is a contentious issue and internationally, there is sharp division whether such labeling ought to be mandatory. This debate has reached India where the government has proposed mandatory labeling.
Ramaswami, Bharat, Bansal, Sangeeta
core  

A universal convolutional neural network for the pixel-level detection and monitoring of weld beads [PDF]

open access: yesComputer Methods in Materials Science
In weld-based manufacturing processes such as welding and metal deposition additive manufacturing (AM), the weld bead is a direct indicator of manufacturing quality.
Zhuo Wang   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Cyclopropene derivatives of aminosugars for metabolic glycoengineering

open access: yesBeilstein Journal of Organic Chemistry, 2019
Cyclopropenes have been proven valuable chemical reporter groups for metabolic glycoengineering (MGE). They readily react with tetrazines in an inverse electron-demand Diels–Alder (DAinv) reaction, a prime example of a bioorthogonal ligation reaction ...
Jessica Hassenrück, Valentin Wittmann
doaj   +1 more source

Use of autologous umbilical cord blood transfusion in neonates undergoing surgical correction of congenital cardiac defects: A pilot study

open access: yesAnnals of Cardiac Anaesthesia, 2018
Background: Blood transfusion requirement during neonatal open heart surgeries is universal. Homologous blood transfusion (HBT) in pediatric cardiac surgery is used most commonly for priming of cardiopulmonary bypass (CPB) system and for postoperative ...
Kunal Sarin   +5 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Edge Vertex Prime Labeling for K2,n and K3,n Graphs [PDF]

open access: yes, 2018
In my study, I inspect edge vertex prime labeling of some graphs like complete bipartite graphs K2,n & K 3,n .
Yamini M Parmar
core   +1 more source

Home - About - Disclaimer - Privacy