Results 61 to 70 of about 641,798 (254)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Square Sum Difference Product Prime Labeling of Some Tree Graphs [PDF]

open access: yes, 2017
Square sum difference product prime labeling of a graph is the labeling of the vertices with {0,1,2---------,p-1} and the edges with absolute difference of the sum of the squares of the labels of the incident vertices and product of the labels of the ...
, Sunoj B S, Mathew Varkey T K
core  

Oblong Mean Prime Labeling of Some Tree Graphs

open access: yes, 2018
The labeling of a graph, we mean assign some integers to the vertices or edges or both of the graph. Here the vertices of the graph are labeled with oblong numbers and the edges are labeled with mean of the end vertex labels.
Mathew Varkey T K, Sunoj B S
core   +1 more source

Neighborhood-prime labeling of some product graphs [PDF]

open access: yes, 2018
We have introduced the concept of neighborhood-prime labeling and investigated it for paths, cycles, wheels and union of such graphs earlier. In this paper, we construct neighborhood-prime labelings for graphs that are cartesian or tensor product of two
Shrimali, N.P., Patel, S.K.
core   +1 more source

Comparative Study of Antimagic Labeling Approaches in Wireless, Interconnection, and Smart Grid Networks

open access: yesJournal of Mathematics
The antimagic labeling of a graph is an important factor of graph theory, which implies the assignment of individual integer values to the graph’s vertices such that all the vertex sums remain unique. Due to the distinctive feature of antimagic labeling,
Poovarasi P, Kavitha K
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

MEAN SUM SQUARE PRIME LABELING OF SOME CYCLE RELATED GRAPHS

open access: yes, 2017
Mean sum square prime labeling of a graph is the labeling of the vertices with {0,1,2---,p-1} and the edges with mean of the square of the sum of the labels of the incident vertices or mean of the square of the sum of the labels of the incident ...
Mathew Varkey T K, Sunoj B S
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

On k-prime graphs

open access: yesOpen Mathematics
In the context of a simple undirected graph GG, a kk-prime labeling refers to assigning distinct integers from the set {k,k+1,…,∣V(G)∣+k−1}\left\{k,k+1,\ldots ,| V\left(G)| +k-1\right\} to its vertices, such that adjacent vertices in GG are labeled with ...
Abughneim Omar A., Abughazaleh Baha’
doaj   +1 more source

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