Results 91 to 100 of about 2,726,364 (271)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
On Prime Near-rings with Generalized (?, ?)-derivations
, 2005 Let N be a prime left near-ring with multiplicative center Z and f be a generalized (sigma, tau)- derivation associated with d : We prove commutativity theorems in prime near-rings with generalized (sigma, tau ...
Golbasi, Oznur
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A NOTE ON COMPLETELY SEMI-PRIME IDEALS IN NEAR-RINGS
, 2009 The aim of the present paper is to prove that (i) Every completely semi-prime ideal I of N is the intersection of all completely prime ideals of I; and (ii) If I is a completely semi-prime ideal of N, then an ideal P of N is a minimal completely prime ...
Satyanarayana Bhavanari
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
On Derivations In Prime Gamma-Near-Rings
GANIT: Journal of Bangladesh Mathematical Society, 2013 Let N be a non zero-symmetric left ?-near-ring. If N is a prime ?-near-ring with nonzero derivations D1 and D2 such that D1(x)?D2(y) = D2(x)?D1(y) for every x, y?N and ???, then we prove that N is an abelian ?-near-ring. Again if N is a 2-torsion free prime ?-near-ring and D1 and D2 are derivations satisfying D1(x)?D2(y) = D2(x)?D1(y) for every x, y?
Akhil Chandra Paul, Kalyan Kumar Dey
openaire +2 more sources
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source