Results 51 to 60 of about 203 (191)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Commutativity of near-rings with (σ;τ)-derivations

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
In this paper we study some conditions under which a near-ring R admitting a (multiplicative) (σ; τ )-derivation d must be a commutative ring with constrained-suitable conditions on d, σ and τ.
Kamal Ahmed A. M., Al-Shaalan Khalid H.
doaj   +1 more source

Acts Freely on Prime and semi prime -near Rings

open access: yesIOSR Journal of Mathematics, 2014
Let M be a -near ring. An element aM is called a dependent element on a mapping f if f(x)αa= ax for all xM, α. In this paper we study and investigate concerning dependent elements of M by certain mappings on prime and semi prime -near rings using certain assumption (A), and also we study the generalized -derivation F of -near ring M and ...
Afrah M Ibraheem, Ahlam J. Lazem
openaire   +1 more source

PRIME GAMMA NEAR-RINGS WITH DERIVATIONS [PDF]

open access: yesInternational Journal of Pure and Apllied Mathematics, 2013
Let N be a prime Γnear-ring with the center Z(N). The objective of this paper is to study derivations on N. We prove two results: (a) Let N be 2-torsion free and let D1 and D2 be derivations on N such that D1D2 is also a derivation. Then D1 = 0 or D2 = 0 if and only if[D1(x), D2(y)]α = 0 for all x, y ∈ N, α ∈ Γ; b) Let n be an integer greater than 1,
Rakhimov, Isamiddin Sattarovich   +2 more
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Great Expectations: Plans and Predictions for New Horizons Encounter With Kuiper Belt Object 2014 MU69 (“Ultima Thule”)

open access: yesGeophysical Research Letters, 2018
The New Horizons encounter with the cold classical Kuiper Belt object 2014 MU69 (informally named “Ultima Thule,” hereafter Ultima) on 1 January 2019 will be the first time a spacecraft has ever closely observed one of the free‐orbiting small denizens of
Jeffrey M. Moore   +33 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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