Results 181 to 190 of about 1,802,459 (260)

The choice is yours: Binding and retrieval of free-choice responses. [PDF]

Atten Percept Psychophys
Nemeth M, Frings C, Moeller B.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Advancing Psychiatric Safety With the Predictive Risk Identification for Mental Health Events Tool: Retrospective Cohort Study.

JMIR Ment Health
Dolatabadi E, Tamayo Velasquez V, Dabboussi AH, Wen D, Crawford J, Waddell AE, El Morr C.   +6 more
europepmc   +1 more source

A Study on the Structure of Ideal-Based Non-Zero Divisor Graphs Associated with <i>Z</i> _<i>n</i>. [PDF]

F1000Res
Kadem S, Abd Aubad A.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Effect of Cigarette Type and Smoking Behavior on Urinary Metabolite Levels of Tobacco-Associated Toxicants. [PDF]

Chem Res Toxicol
Hendriks MG, Pauwels CGGM, Conklin DJ, Lorkiewicz P, Boots AW, Talhout R, Winkens B, Opperhuizen A, van Schooten FJ, Remels AHV.   +9 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

PE-STAR: prime editing with SOS-triggered and RecJ-augmented repair enables high-efficiency editing in Escherichia coli. [PDF]

Nucleic Acids Res
Duan X, Zhang H, Lv J, Fan X, Liu X, Wang Q, Zhang F, Zhang Q, Liu L, Liang L, Liu R.   +10 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

The Prime Diet Quality Score (PDQS), chronic disease and cause-specific mortality in UK Biobank: a prospective study. [PDF]

Eur J Nutr
Kronsteiner-Gicevic S, Thompson AS, Cordova R, Gaggl M, Woodside JV, Cassidy A, Rohrmann S, Kühn T.   +7 more
europepmc   +1 more source