Results 211 to 220 of about 315,776 (265)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Implications of the FDA's new plausible mechanism framework for the development of a personalized in vivo prime editing platform. [PDF]

open access: yesAm J Hum Genet
Feierman ER   +15 more
europepmc   +1 more source

Whole-genome sequence of a varicella-zoster strain from an immunocompetent pediatric patient with severe herpes zoster. [PDF]

open access: yesMicrobiol Resour Announc
Ortigas-Vasquez A   +5 more
europepmc   +1 more source

A multiplex, prime editing framework for identifying drug resistance variants at scale. [PDF]

open access: yesCell Genom
Abadie FMC   +13 more
europepmc   +1 more source

Enhanced immunogenicity and dose-sparing efficacy of self-amplifying RNA vaccines against seasonal influenza across subtypes. [PDF]

open access: yesEmerg Microbes Infect
Huang M   +30 more
europepmc   +1 more source

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