Results 81 to 90 of about 22,083 (264)
The Rough Intuitionistic Fuzzy Ideals of Intuitionistic Fuzzy Subrings in a Commutative Ring
The aim of this paper is to give some definitions of rough intuitionistic fuzzy ideal, rough intuitionistic fuzzy radical, rough prime (primary) intuitionistic fuzzy ideal and rough semiprime intuitionistic fuzzy ideal of an intuitionistic fuzzy subring,
Prasenjit Mandal, A.S. Ranadive
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
ON THE PRIME RADICAL OF A MODULE OVER A NONCOMMUTATIVE RING
In this paper all rings are associative with identity and all modules are unital left modules. Let \(M\) be a left \(R\)-module. A proper submodule \(N\) of \(M\) is called prime if, for any \(r\in R\) and \(m\in M\) such that \(rRm\subseteq N\), either \(rM\subseteq N\) or \(m\in N\). The prime radical \(\text{rad\,}M\) of a module \(M\) is defined to
Callialp, Fethic, Tekir, Unsal
openaire +5 more sources
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
SP-Domains are Almost Dedekind — A Streamlined Proof
Let D be a domain. By [4], D has “property SP” if every ideal of D is a product of radical ideals. It is natural to consider property SP after studying Dedekind domains, which involve factoring ideals into prime ideals.
Ahmed Malik Tusif
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

