Results 161 to 170 of about 42,209 (310)
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
On the Prime Ideals of the Ring of Entire Functions [PDF]
Let R be the ring of entire functions, and let K be the complex field. In an earlier paper [6], the author investigated the ideal structure of R, particular attention being paid to the maximal ideals.
Henriksen, Melvin
core +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
En este artículo, definimos los submódulos gw-primos de un módulo sobre un anillo conmutativo con identidad. Esta clase de submódulos es una generalización de los submódulos débilmente primos.
Bilgin, Zehra +2 more
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Fitting ideals and module structure [PDF]
Let R be a commutative ring with a 1. Original work by H. Fitting showed how we can associate to each finitely generated E-module a unique sequence of R-ideals, which are known as Fitting Ideals. The aim of this thesis is to undertake an investigation of
Grime, Peter John
core
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Examples of Fully Prime Rings (Group, Ring, Language and Related Areas in Computer Science) [PDF]
A ring R (possibly without identity) in which every ideal is prime (i.e. every proper ideal is a prime ideal and (hence) R is a prime ring) is called a fully prime ring.The talk was in part supported by the RIMS, a Joint Usage/Research Center located in ...
Tsutsui, Hisaya, 筒井, 久弥
core
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source

