Results 151 to 160 of about 44,957 (356)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
On ideals of prime rings involving $n$-skew commuting additive mappings with applications
, 2022 Ci̇hat Abdıoğlu +2 more
openalex +2 more sources
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A Study of Generalized Differential Identities via Prime Ideals
Journal of MathematicsLet R be a ring and P be a prime ideal of R. The aim of this research paper is to delve into the relationship between the structural properties of the quotient ring R/P and the behavior of generalized derivations in a ring R endowed with an involution ...
Ali Yahya Hummdi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
On Chains of prime ideals in ring of semialgebraic funtions
, 2014 In this work, we study the structure of non-refinable chains of prime ideals in the (real closed) rings S(M) and S*(M) of semialgebraic and bounded semialgebraic functions on a semialgebraic set M subset of R-m.
Fernando Galván, José Francisco
core +1 more source
The Probability that Ideals in a Number Ring are k-wise Relatively\n r-Prime [PDF]
, 2018 Ryan D. DeMoss, Brian D. Sittinger
openalex +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Prime Gamma-Near-Rings with sigma-Derivations
, 2014 Kalyan Kumar Dey, A. C. Paul
openalex +2 more sources