Results 131 to 140 of about 42,209 (310)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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On (σ, δ)(S, 1) rings and their extensions [PDF]
Mathematica Moravica, 2017 Let R be a ring, σ an endomorphism of R and δ a σ derivation of R. We recall that R is called an (S, 1)-ring if for a, b _ R, ab = 0 implies aRb = 0. We involve σ and δ to generalize this notion and say that R is a (σ, δ) - (S, 1) ring if for a, b _ R ...
Bhat Kumar Vijay
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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The prime spectrum and the extended prime spectrum of noncommutative rings [PDF]
, 2006 We investigate the prime spectrum of a noncommutative ring and its spectral closure, the extended prime spectrum. We construct a ring for which the prime spectrum is a spectral space different from the extended prime spectrum and we construct a von ...
Tressl, Marcus +2 more
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On S-2-Prime Ideals of Commutative Rings
MathematicsPrime ideals and their generalizations are crucial in numerous research areas, particularly in commutative algebra. The concept of generalization of prime ideals begins with the study of weakly prime ideals.
Sanem Yavuz +3 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
On Classical Prime Near-ring Modules [PDF]
In 2005, M. Behboodi introduced the notion of a classical prime ring module, which he showed is, in general, nonequivalent to a (Dauns) prime ring module. In this paper, we extended the idea of classical primeness to near-ring module.
Juglal, S., Djagba, P.
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
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On Graded Jgr-Prime Submodules
Қарағанды университетінің хабаршысы. Математика сериясыIn this paper, we obtain several results concerning graded Jgr-prime submodules over a commutative graded ring. For example, we give fa characterization of graded Jgr-prime submodules and results related to residual of graded Jgr-prime submodules. Also,
M. Alnimer, K. Al-Zoubi, M. Al-Dolat
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