Results 121 to 130 of about 42,209 (310)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
On Chains of prime ideals in ring of semialgebraic funtions [PDF]
, 2014 In this work, we study the structure of non-refinable chains of prime ideals in the (real closed) rings S(M) and S*(M) of semialgebraic and bounded semialgebraic functions on a semialgebraic set M subset of R-m.
Fernando Galván, José Francisco
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Another Proof of Levitzki’s Theorem for Prime Rings and Application to k-skew Commuting Property
AxiomsIn this paper, we provide another proof of Levitzki’s theorem for prime rings with k!-torsion-free using the Vandermonde determinant, which states that a prime ring contains no nonzero nilpotent left or right ideal.
Yazhou Zhang
doaj +1 more source
Approximaitly Semi-Prime Submodules and Some Related Concepts
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2019 We introduce in this paper the concept of approximaitly semi-prime submodules of unitary left -module over a commutative ring with identity as a generalization of a prime submodules and semi-prime submodules, also generalization of quasi-prime ...
Ali Sh. Ajeel, Haibat K. Mohammad ali
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A NOTE ON AUTOMORPHISMS OF PRIME RINGS
Demonstratio Mathematica, 1996 In [Acta Sci. Math. 56, No. 3-4, 369-375 (1992; Zbl 0792.16033)] the reviewer proved that if automorphisms \(\alpha\) and \(\beta\) of a prime ring \(R\) of characteristic not 2 commute and satisfy \(\alpha+\alpha^{-1}=\beta+\beta^{-1}\), then either \(\alpha=\alpha^{-1}\) or \(\beta=\beta^{-1}\).
Chaudhry, A., Thaheem, A. B.
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The Conversion of 5,5′-Bi(1,2,3-dithiazolylidenes) into Isothiazolo[5,4-d]isothiazoles
Molecules, 2018 Thermolysis of 4,4′-dichloro-, 4,4′-diaryl-, and 4,4′-di(thien-2-yl)-5,5′-bi(1,2,3-dithiazol-ylidenes) affords the respective 3,6-dichloro-, 3,6-diaryl- and 3,6-di(thien-2-yl)isothiazolo[5,4-d]-isothiazoles in low to high yields ...
Lidia S. Konstantinova +7 more
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Nilpotency of derivations in prime rings [PDF]
Proceedings of the American Mathematical Society, 1995 In 1957, E. C. Posner proved that if λ \lambda
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