Results 201 to 210 of about 323,998 (369)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Editorial: Unifying Insights into the Desiccation Tolerance Mechanisms of Resurrection Plants and Seeds

open access: yesFrontiers in Plant Science, 2020
Jill M. Farrant   +2 more
doaj   +1 more source

Successive nitric oxide and lipoic acid priming mitigates [ZnO]NPs toxicity in wheat: experimental and DFT insights. [PDF]

open access: yesSci Rep
El Shazoly RM   +5 more
europepmc   +1 more source

Requirement of Newly Synthesized Protein for the Priming Activity of Interferon [PDF]

open access: bronze, 1975
Fumiaki Ito   +2 more
openalex   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Priming of plant innate immunity by rhizobacteria and ß-aminobutyric acid: differences and similarities in regulation.

open access: yes, 2009
Pseudomonas fluorescens WCS417r bacteria and beta-aminobutyric acid can induce disease resistance in Arabidopsis, which is based on priming of defence.
Pieterse, C.M.J.   +6 more
core  

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