Results 31 to 40 of about 2,679 (259)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
‘‘Thus we forever see the ages as they appear mirrored in our spirits”: Willhelm Worringer’s Abstraction and Empathy as longseller, or the birth of artistic modernism from the spirit of the imagined 0ther [PDF]
As welcome as Worringer’s plea for a global broadening of art-historical research may seem from the present perspective, his theoretical approach, which is tied to a fictive other and determined by primitivist ideas remains problematic.
Ursula Helg
doaj
0257 A Half-Hearted Expressionist Extortion
This article traces the genealogy of Expressionism in Uruguay as an artistic form that, within the framework of a figurative art trend of social and popular orientation, questioned the hegemonic guidelines regarding the cultural identity under ...
María Frick
doaj +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
This paper analyses the visions of totalitarian futures in two works written in the interwar period, namely Lewis Grassic Gibbon’s Gay Hunter (1934) and Antoni Słonimski’s Two Ends of the World (1937).
Katarzyna Pisarska
doaj +1 more source
Éloge du primitivisme : d’autres visages de la peinture japonaise prémoderne
In the 1920s, the intellectual Yanagi Muneyoshi (1889–1961) began a rereading of the arts of Japan that would lead to a significant movement of recognition and revitalization of folk art, under the name Mingei. This article revisits Yanagi’s undertaking,
Christophe Marquet
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Archigram in Monte Carlo and the idea of equipped landscape
In 1970, Archigram wins the competition for the entertainment center of Monte Carlo, Monaco. The jury’s profile could explain the sympathy for sophisticated technological solutions, the sort of response that could be expected from Archigram. And it would
Claudia Costa Cabral
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Multidimensional Properties: Primitivism vs Reductionism
The focus of this paper is on the metaphysical nature of multidimensional properties, properties like virtue, beauty, or health which can be had in different ways and to different degrees.
Robert Michels
doaj +1 more source

