Results 41 to 50 of about 456 (257)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Dzieło sztuki na granicy przeszłości i przyszłości. Historia i patriotyzm w sztuce nieprofesjonalnej
A work of art – a link between the present and the past. History and patriotism in non-professional art In her article, the author discusses art of non-professional artists who shape the national identity in an original way. In the former professional
Aleksandra Weronika Jarysz
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Sonic Others in Early Sound Studies and the Poetry of Edward Sapir
Characteristically, early research in soundscapes is suffused with a sense of sonophilia; that is, a fascination with auditory perception and sound as the inferiorized Other of sight.
Elisabeth A. Reichel
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
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Martha Graham, ‘An American, A kosmos’: Border-crossing in Martha Graham’s early works
This paper examines the connection between crossing borders (state limits, borders between America and Mexico or America and Europe, and temporal borders) and pushing choreographical boundaries in dance pioneer Martha Graham’s ballets created in the 1930’
Adeline CHEVRIER-BOSSEAU
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Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
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In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
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Though recent historiography has paid little attention to fauvism as a historical movement, a number of exhibition catalogues on the subject have been published over the past twenty years.
Claudine Grammont
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Social construction of “other” as “primitive” [PDF]
The author of this paper deals with the problem of cultural difference through the analysis of the relationship “us” - “others”. He searches for the answer to the question why the culture of other peoples or individuals are often considered inferior ...
Božilović Nikola T.
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