Results 41 to 50 of about 250,431 (241)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Social network learning efficiency in the principal–agent relationship
Journal of Management Science and EngineeringUnder the bounded rationality assumption, a principal rarely provides an optimal contract to an agent. Learning from others is one way to improve such a contract.
Chuan Ding +3 more
doaj +1 more source
Mathematics, 2023 Liquidated damages mechanisms have been analyzed from a legal perspective and applied to real-world contracts. Due to the lack of application of LDs to common agency theory, this research explores whether the liquidated damages mechanism can resolve ...
Yuxun Zhou +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Reinvention and the Principal-Agent Model
Convergencia, 2003 Existe una interesante polémica en el sector público, derivada de las tensiones existentes entre desempeño y flexibilidad administrativa por un lado, y rendición de cuentas y control, por el otro.
J. Ramón Gil García
doaj
Anti-Trafficking Interventions in Nigeria and the Principal-Agent Aid Model
Anti-Trafficking Review, 2014 Following the rising profile of trafficking in persons globally and Nigeria’s position as a critical country in the African region, significant—though insufficient and poorly spent—funding has been deployed towards tackling the problem.
Victoria Ijeoma Nwogu
doaj +1 more source
Cogent Business & Management, 2023 This study aims to analyse the details of the stages in the decision-making process of real estate agents to reconcile the landlords and expatriate tenants’ criteria and to explain these relationships with the principal-agent theory.
Niti Rattanaprichavej
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
CIVIL LIABILITY OF PRINCIPAL FOR THE ACTS OF AGENT – A COMPARISON BETWEEN FRANCE AND MAURITIUS
Anali Pravnog Fakulteta u BeograduMauritian civil law is strongly influenced by French civil law, for historical reasons. Civil liability, tort and contractual law, is regulated in an almost same manner in the two countries.
Goran GEORGIJEVIĆ
doaj +1 more source