Results 41 to 50 of about 587,884 (267)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Relevance of the Principal-Agent Model for the Analysis of Public Policies : Do the Objectives Conflict ? [PDF]
, 2007 This paper aims to provide empirical support for the use of the principal-agent framework in the analysis of public sector and public policies. After reviewing the different conditions to be met for a relevant analysis of the relationship between ...
Chatagny, F., Soguel, N.
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The Principal-Agent Model with an Informative Signal to the Advantage of the Agent [PDF]
Problemi Ekonomiki, 2019 This article deals with the problem of negative impact of information asymmetry on the market and methods for mitigating it. This problem is solved by using the methods of the economic theory of contracts.
Nykyforchyn Iryna V.
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Journal of Public Administration and Development Alternatives, 2020 The obstinate problem of non-compliance with municipal finance legislation in South Africa has been largely explained as a principal-agent problem. Accordingly, the municipal officials as agents are depicted as potentially non-compliant, dishonest, and ...
T Khaile
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
World Electric Vehicle JournalThis study investigates how the government can design optimal incentive mechanisms for Shared Battery Swapping Station (SBSS) construction enterprises under the conditions of dual information asymmetry (effort and operational efficiency) and ...
Lei He +3 more
doaj +1 more source
Principle – Agent Model for Sleeping Partnership Moral hazard [PDF]
Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2011 Game theory has a significant role in contemporary orthodox economics. This theory studies the strategic behavior of players. So strategic interaction is the key point in the games theory. Principalagent model is an application of the theory. This model
Mohammad Hadi Zahidi Vafa +1 more
doaj
Structural estimation of a principal-agent model: moral hazard in medical insurance [PDF]
, 2003 Despite the importance of principal-agent models in the development of modern economic theory, there are few estimations of these models. I recover the estimates of a principal-agent model and obtain an approximation to the optimal contract.
Vera-Hernandez, M
core +1 more source