Results 91 to 100 of about 658,976 (287)
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Kontrak Usaha Pemanfaatan Wisata Alam pada Kesatuan Pengelolaan Hutan Lindung Rinjani Barat
Journal of Natural Resources and Environmental Management, 2019 Partnership in natural tourism utilization of protected forests area can increase the forests value, but also has a risk of damage to forest areas managed by KPHL Rinjani West (FMU).
Muhammad Rifqi Tirta Mudhofir +2 more
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
ASPECTS REGARDING INTERNATIONAL RESPONSIBILITY BY ANALYSING THE AGENCY RELATIONSHIP BETWEEN THE INTERNATIONAL ORGANIZATION AND THE STATE [PDF]
Challenges of the Knowledge Society, 2016 The study analyses the consequences for the responsibility of the organization and the relevant state of an agency relationship between an international organization acting as a principal and a state acting as its agent.
Ovidiu-Emilian IVĂNESCU
doaj
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
The legal governance of the carbon market: challenges and application of private law in China
Carbon ManagementThe carbon market has gained widespread consensus as an important means to address the climate change. The legal system of the carbon market is the cornerstone of the stable operation, which currently relies on a top-down model promoted by the government.
Bo Chen, Kang Yuan, Xuwu Wen
doaj +1 more source
Who is Running the IMF: Critical Shareholders or the Staff? [PDF]
The paper deals with the principal-agent relationship at the International Monetary Fund (IMF). We argue that residual control rights at the IMF are vested with the critical shareholders, the countries included in the G-7.
John Pattison, Michele Fratianni
core
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
A Principal-Agent Model of Sequential Testing [PDF]
This paper analyzes the optimal provision of incentives in a sequential testing context. In every period the agent can acquire costly information that is relevant to the principal's decision. Neither the agent's effort nor the realizations of his signals
Dino Gerardi, Lucas Maestri
core +3 more sources
Incentives for Experimenting Agents [PDF]
We examine a repeated interaction between an agent, who undertakes experiments, and a principal who provides the requisite funding for these experiments.
Johannes Horner, Larry Samuelson
core