Results 101 to 110 of about 1,854,699 (363)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Parabolic principal Higgs bundles [PDF]

open access: yesarXiv, 2008
In ``Ramified G-bundles as parabolic bundles'' (J. Ramanujan Math. Soc. (2003) Vol. 18) with Balaji and Nagaraj we introduced the ramified principal bundles. The aim here is to define the Higgs bundles in the ramified context.
arxiv  

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Geometry of frame bundles

open access: yesLietuvos Matematikos Rinkinys
In this article we define the canonical forms on the principal bundle of holonomic frames of order r, give structure equations for these forms and determine the connection of order r.
Kazimeras Navickis
doaj   +1 more source

Construction of Categorical Bundles from Local Data [PDF]

open access: yesarXiv, 2016
A categorical principal bundle is a structure comprised of categories that is analogous to a classical principal bundle; examples arise from geometric contexts involving bundles over path spaces. We show how a categorical principal bundle can be constructed from local data specified through transition functors and natural transformations.
arxiv  

Lectures on Principal Bundles [PDF]

open access: yes, 2009
To Peter Newstead on his 65th birthday Introduction The aim of these lectures is to give a brief introduction to principal bundles on algebraic curves towards the construction of the moduli spaces of semistable principal bundles. The second section develops the basic machinery on principal bundles and their automorphisms.
openaire   +2 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

An Introduction to Pull-backs of Bundles and Homotopy Invariance [PDF]

open access: yesarXiv, 2001
We define the pull-back of a smooth principal fibre bundle, and show that it has a natural principal fibre bundle structure. Next, we analyse the relationship between pull-backs by homotopy equivalent maps. The main result of this article is to show that for a principal fibre bundle over a paracompact manifold, there is a principal fibre bundle ...
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

A compactification of the moduli space of principal Higgs bundles over singular curves [PDF]

open access: yesarXiv, 2011
A principal Higgs bundle $(P,\phi)$ over a singular curve $X$ is a pair consisting of a principal bundle $P$ and a morphism $\phi:X\to\text{Ad}P \otimes \Omega^1_X$. We construct the moduli space of principal Higgs G-bundles over an irreducible singular curve $X$ using the theory of decorated vector bundles.
arxiv  

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