Results 101 to 110 of about 1,854,699 (363)
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Parabolic principal Higgs bundles [PDF]
In ``Ramified G-bundles as parabolic bundles'' (J. Ramanujan Math. Soc. (2003) Vol. 18) with Balaji and Nagaraj we introduced the ramified principal bundles. The aim here is to define the Higgs bundles in the ramified context.
arxiv
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
In this article we define the canonical forms on the principal bundle of holonomic frames of order r, give structure equations for these forms and determine the connection of order r.
Kazimeras Navickis
doaj +1 more source
Construction of Categorical Bundles from Local Data [PDF]
A categorical principal bundle is a structure comprised of categories that is analogous to a classical principal bundle; examples arise from geometric contexts involving bundles over path spaces. We show how a categorical principal bundle can be constructed from local data specified through transition functors and natural transformations.
arxiv
Lectures on Principal Bundles [PDF]
To Peter Newstead on his 65th birthday Introduction The aim of these lectures is to give a brief introduction to principal bundles on algebraic curves towards the construction of the moduli spaces of semistable principal bundles. The second section develops the basic machinery on principal bundles and their automorphisms.
openaire +2 more sources
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens+8 more
wiley +1 more source
An Introduction to Pull-backs of Bundles and Homotopy Invariance [PDF]
We define the pull-back of a smooth principal fibre bundle, and show that it has a natural principal fibre bundle structure. Next, we analyse the relationship between pull-backs by homotopy equivalent maps. The main result of this article is to show that for a principal fibre bundle over a paracompact manifold, there is a principal fibre bundle ...
arxiv
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
A compactification of the moduli space of principal Higgs bundles over singular curves [PDF]
A principal Higgs bundle $(P,\phi)$ over a singular curve $X$ is a pair consisting of a principal bundle $P$ and a morphism $\phi:X\to\text{Ad}P \otimes \Omega^1_X$. We construct the moduli space of principal Higgs G-bundles over an irreducible singular curve $X$ using the theory of decorated vector bundles.
arxiv