Results 111 to 120 of about 2,390,711 (295)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On the Đurđević approach to quantum principal bundles
Journal of Geometry and Physics45 pages; corrected equation (206); added "Quantum Symmetries" to acknowledgements; added journal reference for [11]
Del Donno A., Latini E., Weber T.
openaire +3 more sources
Prescribing the curvature of a principal bundle connection
, 1989 This thesis considers the problem of prescribing curvature for connections on principal bundles. As is well known, a connection on a principal bundle uniquely determines the curvature of that bundle.
Talvacchia, Janet Claire
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Revista de Epidemiologia e Controle de InfecçãoJustificativa e Objetivos: infecções de pele podem ocorrer em pacientes com queimaduras devido à perda da principal barreira protetora e imunológica. Apesar de existir protocolos gerais para tratamento de queimaduras e prevenção de infecção, poucos são ...
Daiane Mendes Ribeiro +5 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Principal Bundles and Gauge Theories
, 2011 This set of lecture notes first gives an introduction to the geometry of principal bundles. Next, it demonstrates how they can be used to formalize the concept of gauge theories arising in physics. A basic familiarity with the differential geometry of manifolds and the classical field theories of general relativity and electromagnetism is assumed.
openaire +3 more sources
Extensions of the Principal Fiber Bundle Model for Locomoting Robots
, 2018 Our goal is to establish a rigorous formulation for modeling the locomotion of a broad class of robotic systems. Recent research has identified a number of systems with the structure of a principal fiber bundle.
Tony Dear (4946827)
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source