Results 101 to 110 of about 200,107 (280)

On very stablity of principal G-bundles [PDF]

open access: yesGeometriae Dedicata, 2019
Let $X$ be a smooth irreducible projective curve. Recently, Pauly and Peón-Nieto shows that a vector bundle over $X$ is very stable if and only if the Hitchin map on the vector space of Higgs field on that vector bundle is proper. In this notes, we generalize this result to principal $G-$bundles for any semisimple linear algebraic group $G$.
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

ECG signal classification method based on improved BP neural network

open access: yesDianzi Jishu Yingyong, 2019
Accurate identification of ECG signals is the key to intelligent diagnosis of ECG monitoring systems. In order to improve the classification accuracy of ECG signals, an improved ECG signal classification algorithm based on BP neural network was studied ...
Wang Li, Guo Xiaodong, Hui Yanbo
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Construção e validação de bundle para prevenção de infecção de pele por queimaduras: estudo metodológico

open access: yesRevista de Epidemiologia e Controle de Infecção
Justificativa e Objetivos: infecções de pele podem ocorrer em pacientes com queimaduras devido à perda da principal barreira protetora e imunológica. Apesar de existir protocolos gerais para tratamento de queimaduras e prevenção de infecção, poucos são ...
Daiane Mendes Ribeiro   +5 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Conhecimento e adesão às medidas preventivas da pneumonia associada à ventilação mecânica na pandemia de COVID-19

open access: yesRevista de Epidemiologia e Controle de Infecção
Justificativa e Objetivos: a COVID-19 aumentou a demanda pela terapia intensiva e intensificou a necessidade de ventilação mecânica e a gravidade da pneumonia associada à ventilação mecânica (PAV).
Hélio Galdino Júnior   +3 more
doaj   +1 more source

On the Đurđević approach to quantum principal bundles

open access: yesJournal of Geometry and Physics
45 pages; corrected equation (206); added "Quantum Symmetries" to acknowledgements; added journal reference for [11]
Del Donno A., Latini E., Weber T.
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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