Results 111 to 120 of about 1,854,699 (363)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Homogeneous principal bundles and stability [PDF]

open access: yesForum Mathematicum, 2010
Let G/P be a rational homogeneous variety, where P is a parabolic subgroup of a simple and simply connected linear algebraic group G defined over an algebraically closed field of characteristic zero. A homogeneous principal bundle over G/P is semistable (respectively, polystable) if and only if it is equivariantly semistable (respectively ...
openaire   +3 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Bundles over Quantum RealWeighted Projective Spaces

open access: yesAxioms, 2012
The algebraic approach to bundles in non-commutative geometry and the definition of quantum real weighted projective spaces are reviewed. Principal U(1)-bundles over quantum real weighted projective spaces are constructed.
Tomasz Brzeziński, Simon A. Fairfax
doaj   +1 more source

Principal bundles under reductive groups [PDF]

open access: yesarXiv, 2015
Let $k$ be a field of characteristic $0$. We consider principal bundles over a $k$-scheme with reductive structure group (not necessarily of finite type). It is showm in particular that for $k$ algebraically closed there exists on any complete connected $k$-scheme a universal such bundle.
arxiv  

Deformation quantization of principal bundles [PDF]

open access: yesInternational Journal of Geometric Methods in Modern Physics, 2016
We outline how Drinfeld twist deformation techniques can be applied to the deformation quantization of principal bundles into noncommutative principal bundles and, more in general, to the deformation of Hopf–Galois extensions. First, we twist deform the structure group in a quantum group, and this leads to a deformation of the fibers of the principal ...
openaire   +4 more sources

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

On connections on principal bundles [PDF]

open access: yesarXiv, 2016
A new construction of a universal connection was given in \cite{BHS}. The main aim here is to explain this construction. A theorem of Atiyah and Weil says that a holomorphic vector bundle $E$ over a compact Riemann surface admits a holomorphic connection if and only if the degree of every direct summand of $E$ is degree.
arxiv  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Criterion for connections on principal bundles over a pointed Riemann surface

open access: yesComplex Manifolds, 2017
We investigate connections, and more generally logarithmic connections, on holomorphic principal bundles over a compact connected Riemann surface.
Biswas Indranil
doaj   +1 more source

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