Results 131 to 140 of about 2,005,987 (380)

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Geometry of frame bundles

open access: yesLietuvos Matematikos Rinkinys
In this article we define the canonical forms on the principal bundle of holonomic frames of order r, give structure equations for these forms and determine the connection of order r.
Kazimeras Navickis
doaj   +1 more source

Construction of Categorical Bundles from Local Data [PDF]

open access: yesarXiv, 2016
A categorical principal bundle is a structure comprised of categories that is analogous to a classical principal bundle; examples arise from geometric contexts involving bundles over path spaces. We show how a categorical principal bundle can be constructed from local data specified through transition functors and natural transformations.
arxiv  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

An Introduction to Pull-backs of Bundles and Homotopy Invariance [PDF]

open access: yesarXiv, 2001
We define the pull-back of a smooth principal fibre bundle, and show that it has a natural principal fibre bundle structure. Next, we analyse the relationship between pull-backs by homotopy equivalent maps. The main result of this article is to show that for a principal fibre bundle over a paracompact manifold, there is a principal fibre bundle ...
arxiv  

Connections on the path bundle of a principal fiber bundle

open access: yesDifferential Geometry and its Applications, 1994
AbstractLet (P, M, π, G) be a principal fiber bundle. In the first section of this paper, we consider the Fréchet manifold PP of smooth paths in P along with important Fréchet submanifolds such as the space PP of paths in P which emanate from some fixed point u0 ∈ P and the space π∗u0(Lx0M) of paths at u0 in P which project to the set Lx0M of loops of ...
openaire   +2 more sources

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

A compactification of the moduli space of principal Higgs bundles over singular curves [PDF]

open access: yesarXiv, 2011
A principal Higgs bundle $(P,\phi)$ over a singular curve $X$ is a pair consisting of a principal bundle $P$ and a morphism $\phi:X\to\text{Ad}P \otimes \Omega^1_X$. We construct the moduli space of principal Higgs G-bundles over an irreducible singular curve $X$ using the theory of decorated vector bundles.
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

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