Results 131 to 140 of about 193,300 (324)
Differential Geometric Structures on Principal Toroidal Bundles [PDF]
, 1973 David E. Blair +2 more
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Hierarchy of spaces of projective connection
Дифференциальная геометрия многообразий фигур, 2018 We consider the bundle of projective frames over a smooth manifold, i. e. the principal bundle whose typical fiber is the projective group. The giving fundamental-group connection in this bundle transforms it into a space of general projective connection.
Yu. Shevchenko
doaj
Characteristic Classes of Foliated Principal $GL_{r}$-Bundles [PDF]
, 1975 Haruo Suzuki
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
On synthetic interpretation of quantum principal bundles
, 2009 Quantum principal bundles or principal comodule algebras are re-interpreted as principal bundles within a framework of Synthetic Noncommutative Differential Geometry.
Brzeziński, Tomasz
core
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
A groupoid approach to noncommutative T-duality
, 2007 Topological T-duality is a transformation taking a gerbe on a principal torus bundle to a gerbe on a principal dual-torus bundle. We give a new geometric construction of T-dualization, which allows the duality to be extended in following two directions ...
Daenzer, Calder
core +3 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source