Results 81 to 90 of about 198,779 (330)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Advances in Mathematical Physics, 2017 This paper gives an introduction to certain classical physical theories described in the context of locally Minkowskian causal structures (LMCSs). For simplicity of exposition we consider LMCSs which have locally Euclidean topology (i.e., are manifolds ...
John Mashford
doaj +1 more source
Moduli spaces of framed $G$--Higgs bundles and symplectic geometry
, 2019 Let $X$ be a compact connected Riemann surface, $D\, \subset\, X$ a reduced effective divisor, $G$ a connected complex reductive affine algebraic group and $H_x\, \subsetneq\, G_x$ a Zariski closed subgroup for every $x\, \in\, D$. A framed principal $G$-
Biswas, Indranil +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Loop Groups, Kaluza-Klein Reduction and M-Theory
, 2004 We show that the data of a principal G-bundle over a principal circle bundle is equivalent to that of a \hat{LG} = U(1) |x LG bundle over the base of the circle bundle.
A. Adams +24 more
core +1 more source
Geometry of quantum principal bundles I [PDF]
Communications in Mathematical Physics, 1996 A general non-commutative-geometric theory of principal bundles is developed. Quantum groups play the role of structure groups and general quantum spaces play the role of base manifolds. A general conceptual framework for the study of differential structures on quantum principal bundles is presented.
openaire +4 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Construction of an A-manifold on a principal torus bundle
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2013 We construct a new example of an A-manifold, i.e. a Riemannian manifold with cyclic-parallel Ricci tensor. This condition can be viewed as a generalization of the Einstein condition.
Grzegorz Zborowski
doaj
, 2019 The bigerbes introduced here give a refinement of the notion of 2-gerbes, representing degree four integral cohomology classes of a space. Defined in terms of bisimplicial line bundles, bigerbes have a symmetry with respect to which they form 'bundle 2 ...
Kottke, Chris, Melrose, Richard B.
core +1 more source