Results 251 to 260 of about 2,261,156 (339)

Comparison between compositional data analysis and principal component analysis for identifying dietary patterns associated with hyperuricemia. [PDF]

Front Nutr
Zhao J, Zhao Y, Han J, Zhao Y, Liu S, Liu Z, Zhang L, Zhang Y.   +7 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A novel hybrid model for species distribution prediction using probabilistic random forest, principal component analysis and genetic algorithm. [PDF]

PLoS One
Adekunle TA, Ogundoyin IK, Akanbi CO.
europepmc   +1 more source

Beyond Regularization: Inherently Sparse Principal Component Analysis [PDF]

Jan O. Bauer
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Position-specific workload and performance analysis in professional rugby union: Insights from global positioning system data and principal component analysis. [PDF]

PLoS One
Ren X, Boisbluche S, Philippe K, Demy M, Hu Z, Ding S, Prioux J.   +6 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cognitive modes involved in emotion regulation identified using Constrained Principal Component Analysis for fMRI (fMRI-CPCA)

van Reekum CM, Tupitsa E, Lloyd WK, Momeni A, Shahki J, Feredoes E, Woodward TS.   +6 more
europepmc   +1 more source

Principal Component Analysis Based Quaternion-Valued Medians for Non-Invasive Blood Glucose Estimation. [PDF]

Sensors (Basel)
Feng J, Ling BW.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source