Results 151 to 160 of about 811,918 (310)

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Identifying patterns of climate variability from Principal Component Analysis – PCA, Fourier y k-means clustering

Tecnura, 2017
Context: Is achieved a research through Principal Component Analysis (PCA) for determining the variability and climate patterns of two important cities in the Colombia Caribbean.
Juan Gabriel Rueda Bayona, Cindy Judith Elles-Pérez, Edgar Humberto Sánchez Cotte, Ángel León López Ariza, Germán Rivillas   +4 more
doaj  

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

Advanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu   +10 more
wiley   +1 more source

PCA (principal component analysis) [PDF]

, 2008
openaire   +2 more sources

Integration of Response Surface Methodology (RSM) and Principal Component Analysis (PCA) as an Optimization Tool for Polymer Inclusion Membrane Based-Optodes Designed for Hg(II), Cd(II), and Pb(II). [PDF]

Membranes (Basel), 2021
García-Beleño J, Rodríguez de San Miguel E.   +1 more
europepmc   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

PENERAPAN METODE PRINCIPAL COMPONENT ANALYSIS (PCA) UNTUK DETEKSI ANOMALI PADA JARINGAN PEER-TO-PEER (P2P) BOTNET

Techno.Com, 2015
Sejak kemunculan peer-to-peer (P2P) Command and Control (C&C) arsitektur, botnet menjadi lebih kuat dibandingkan sebelumnya. Identifikasi anomali dari P2P botnet sangatlah sulit dilakukan padahal proses tersebut merupakan langkah awal yang sangat ...
Adhitya Nugraha, Nova Rijati
doaj  

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Application of principal component analysis (PCA) as a sensory assessment tool for fermented food products

Journal of food science and technology, 2012
D. Ghosh, P. Chattopadhyay
semanticscholar   +1 more source

A holistic decision-making approach for identifying influential parameters affecting sustainable production process of canola bast fibres and predicting end-use textile choice using principal component analysis (PCA). [PDF]

Heliyon, 2021
Shuvo II.
europepmc   +1 more source