Results 71 to 80 of about 26,186,381 (274)

Stratification of cephalosporins based on physicochemical and pharmacokinetic variables using multivariate statistical tools

open access: yesIntelligent Pharmacy
Introduction: Cephalosporins, a class of beta-lactam antibiotics, are commonly used in medical practice. However, their potential advantages, based on physicochemical and pharmacokinetic variables, are often overlooked.
Carlos Alberto Escobar Angulo   +2 more
doaj   +1 more source

A least squares approach to Principal Component Analysis for interval valued data [PDF]

open access: yes
Principal Component Analysis (PCA) is a well known technique the aim of which is to synthesize huge amounts of numerical data by means of a low number of unobserved variables, called components.
D'Urso, Pierpaolo, Giordani, Paolo
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Generalized power method for sparse principal component analysis [PDF]

open access: yes
In this paper we develop a new approach to sparse principal component analysis (sparse PCA). We propose two single-unit and two block optimization formulations of the sparse PCA problem, aimed at extracting a single sparse dominant principal component of
Journée, Michel   +3 more
core  

Principal component analysis and perturbation theory–based robust damage detection of multifunctional aircraft structure [PDF]

open access: yes, 2013
A fundamental problem in structural damage detection is to define an efficient feature to calculate a damage index. Furthermore, due to perturbations from various sources, we also need to define a rigorous threshold whose overtaking indicates the ...
HAJRYA, Rafik, MECHBAL, Nazih
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Robust sparse principal component analysis. [PDF]

open access: yes
A method for principal component analysis is proposed that is sparse and robust at the same time. The sparsity delivers principal components that have loadings on a small number of variables, making them easier to interpret.
Croux, Christophe   +2 more
core  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

TL-PCA: Transfer Learning of Principal Component Analysis

open access: yesCoRR
Principal component analysis (PCA) can be significantly limited when there is too few examples of the target data of interest. We propose a transfer learning approach to PCA (TL-PCA) where knowledge from a related source task is used in addition to the scarce data of a target task. Our TL-PCA has two versions, one that uses a pretrained PCA solution of
Sharon Hendy, Yehuda Dar
openaire   +3 more sources

Image fusion for dynamic contrast enhanced magnetic resonance imaging [PDF]

open access: yes, 2004
Twellmann T, Saalbach A, Gerstung O, Leach MO, Nattkemper TW. Image fusion for dynamic contrast enhanced magnetic resonance imaging. Biomed Eng Online. 2004;3(1): 35.BACKGROUND: Multivariate imaging techniques such as dynamic contrast-enhanced magnetic ...
Nattkemper, Tim Wilhelm ; https://orcid.org/   +23 more
core   +2 more sources

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