Results 121 to 130 of about 690,275 (266)

Pattern Classification Using Secondary Components Perceptron and Economic Applications [PDF]

open access: yes
In this paper we will classify patterns using a modified Perceptron algorithm (Dumitrache et al., 1999). The generalization uses the eigenvalues and the eigenvectors of the sample covariance matrix, as we did for classifying patterns using PCR (Ciuiu ...
Ciuiu, Daniel
core  

Correction for founder effects in host-viral association studies via principal components [PDF]

open access: yes, 2012
Viruses such as HIV and Hepatitis C (HCV) replicate rapidly and with high transcription error rates, which may facilitate their escape from immune detection through the encoding of mutations at key positions within human leukocyte antigen (HLA)-specific ...
James, I.R.   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Principal components [PDF]

open access: yes, 2018
This thesis presents principal components as a useful tool for data dimensio- nality reduction. In the first part, the basic terminology and theoretical properties of principal components are described and a biplot construction is derived there as well ...
Zavadilová, Anna
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

PREDICTABILITY AND COMPLEXITY IN MACROECONOMICS. THE CASE OF GROSS FIXED CAPITAL FORMATION IN THE ROMANIAN ECONOMY [PDF]

open access: yes
There is a relationship between predictability and complexity. The problem of evaluating the complexity of the macroeconomic phenomenon can be reduced to decomposition into its principal components (which may have, in their turn, a certain degree of ...
Saman, Corina   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Principal Components Analysis of Employment in Eastern Europe [PDF]

open access: yes
For the last decade, the employment structure is one of the fastest changing areas of Eastern Europe. This paper explores the best methodology to compare the employment situations in the countries of this region.
Mirko Savić
core  

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