Results 161 to 170 of about 2,337,506 (337)

Principal Component Analysis of Crop Yield Response to Climate Change

, 2011
Ruohong Cai, John C. Bergstrom, Jeffrey D. Mullen, Michael E. Wetzstein, W. Donald Shurley, Cai, Ruohong, Bergstrom, John C., Mullen, Jeffrey D., Wetzstein, Michael E., Shurley, W. Donald   +9 more
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The metabolic spatial covariance pattern of definite idiopathic normal pressure hydrocephalus: an FDG PET study with principal components analysis. [PDF]

Alzheimers Res Ther, 2023
Rau A, Schröter N, Blazhenets G, Maurer C, Urbach H, Meyer PT, Frings L.   +6 more
europepmc   +1 more source

Principal component analysis of measurements in the skeleton of red jungle fowl and 12 breeds of domestic fowls. III. Ossa membri pelvini.

, 1990
Masamichi Samejima
openalex   +2 more sources

Diagnosis of Dry Eye Disease Using Principal Component Analysis: A Study in Animal Models of the Disease [PDF]

, 2021
Robert Honkanen, Barbara Nemesure, Liqun Huang, Basil Rigas   +3 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The Application of Clustering on Principal Components for Nutritional Epidemiology: A Workflow to Derive Dietary Patterns. [PDF]

Nutrients, 2022
Maugeri A, Barchitta M, Favara G, La Mastra C, La Rosa MC, Magnano San Lio R, Agodi A.   +6 more
europepmc   +1 more source

Neural Network Characterization and Entropy Regulated Data Balancing Through Principal Component Analysis

, 2023
David Yevick, Karolina Hutchison
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Initial Steps towards a Multilevel Functional Principal Components Analysis Model of Dynamical Shape Changes. [PDF]

J Imaging, 2023
Farnell DJJ, Claes P.
europepmc   +1 more source