Results 191 to 200 of about 2,229,496 (344)

Hierarchical relations among principal component and factor analysis procedures elucidated from a comprehensive model [PDF]

Kohei Adachi
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Constrained Multivariate Functional Principal Components Analysis for Novel Outcomes in Eye-Tracking Experiments. [PDF]

Stat Biosci
Kwan B, Sugar CA, Qian Q, Shic F, Naples A, Johnson SP, Webb SJ, Jeste S, Faja S, Levin AR, Dawson G, McPartland JC, Şentürk D.   +12 more
europepmc   +1 more source

A noval identification of 4 systemic sclerosis - interstitial lung disease subgroups using principal component analysis-based cluster analysis [PDF]

Yaqi Zhao, Baoting Chao, Wei Xu, Xinya Li, Jin Zhang, Ying Zhang, Zhenzhen Ma, Qingrui Yang   +7 more
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SISTEM PRESENSI PENGENALAN WAJAH DENGAN METODE PRINCIPAL COMPONENT ANALYSIS (PCA)

, 2021
EKO SUDARYANTO, ASEP SURYANTO
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

A Principal Components Analysis and Functional Annotation of Differentially Expressed Genes in Brain Regions of Gray Rats Selected for Tame or Aggressive Behavior. [PDF]

Int J Mol Sci
Chadaeva I, Kozhemyakina R, Shikhevich S, Bogomolov A, Kondratyuk E, Oshchepkov D, Orlov YL, Markel AL.   +7 more
europepmc   +1 more source

Mapping Human Vulnerability to Extreme Heat: A Critical Assessment of Heat Vulnerability Indices Created Using Principal Components Analysis. [PDF]

Environ Health Perspect, 2020
Conlon KC, Mallen E, Gronlund CJ, Berrocal VJ, Larsen L, O'Neill MS.   +5 more
europepmc   +1 more source

Optimizing Taiwan’s Renewable Energy Mix: A Regression and Principal Component Analysis Approach Under Climate Change Challenges [PDF]

Mei-Mei Lin
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Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source