Results 201 to 210 of about 2,259,407 (341)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Principal Component Analysis of Crop Yield Response to Climate Change

, 2011
Ruohong Cai, John C. Bergstrom, Jeffrey D. Mullen, Michael E. Wetzstein, W. Donald Shurley, Cai, Ruohong, Bergstrom, John C., Mullen, Jeffrey D., Wetzstein, Michael E., Shurley, W. Donald   +9 more
openalex   +2 more sources

Statistical analysis of astro-geodetic data through principal component analysis, linear modelling and bootstrap based inference [PDF]

, 2018
Andreea Ioana Gornea, Alexandru Cǎlin, Paul Daniel Dumitru, Dan Alin Nedelcu, Radu S. Stoica   +4 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Exploring Population Structure with Admixture Models and Principal Component Analysis. [PDF]

Methods Mol Biol, 2020
Liu CC, Shringarpure S, Lange K, Novembre J.   +3 more
europepmc   +1 more source

Principal Component and Cluster Analysis of Fibre Yield in Roselle (Hibiscus sabdariffaL.)

, 2014
Hariram Kumar Bandi, A. Appalaswamy
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PRINCIPAL COMPONENT ANALYSIS AND MORPHOSTRUCTURAL CHARACTERIZATION OF A PORTION OF THE EASTERN CONTINENTAL SHELF OF CEARÁ, BRAZIL, USING LANDSAT 5-TM IMAGES

, 2016
Cynthia Romariz Duarte, Elicius Feijó Cordeiro, José Higor Batista Araujo Costa, José Antônio Beltrão Sabadia, Ana Rita Salgueiro, Michael Vandesteen Silva Souto, Wellington Ferreira Silva Filho   +6 more
openalex   +2 more sources

Comparative analysis of principal components can be misleading

bioRxiv, 2014
J. Uyeda, Daniel S. Caetano, Matthew W. Pennell   +2 more
semanticscholar   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source