Results 91 to 100 of about 2,147,453 (288)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
ITERATIVE AGGREGATION METHOD FOR SOLVING PRINCIPAL COMPONENT ANALYSIS PROBLEMS
International Journal for Computational Civil and Structural Engineering, 2017 Motivated by the previously developed multilevel aggregation method for solving structural analysis problems a novel two-level aggregation approach for efficient iterative solution of Principal Component Analysis (PCA) problems is proposed.
Vitaly E. Bulgakov
doaj +1 more source
Sharing with a risk-neutral agent [PDF]
In the standard solution to the principal–agent problem, a risk-neutral agent bears all the risk. The author shows that, in fact, multiple solutions exist, and often the risk-neutral agent is not the sole bearer of risk. As risk aversion approaches zero,
Joseph G. Haubrich
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Existence of a solution to the principal's problem [PDF]
Brazilian Review of Econometrics, 1987 This article deals with the existence of a solution to the Principal Agent Problem. Here we develops some basic results with the aid of Berge's Maximum Theorem. Also, a presentation of some interesting examples is given.
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
On the negative coupling O(N) model in 2d at high temperature
Journal of High Energy PhysicsIn this work, I consider N-component scalar quantum field theory in two dimensions interacting with an upside-down quartic potential. Working in the large N limit, the model can be solved non-perturbatively using the saddle-point method for sufficiently ...
Paul Romatschke
doaj +1 more source
International Journal of Concrete Structures and Materials, 2019 While internal and external unbonded tendons are widely utilized in concrete structures, an analytical solution for the increase in unbonded tendon stress at ultimate strength, $$\Delta f_{ps}$$ Δfps , is challenging due to the lack of bond between ...
Eric McKinney +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Regresion PLS y PCA como Solucion al Problema de Multicolinealidad en Regresion Multiple
Revista de Matemática: Teoría y Aplicaciones, 2011 We present and compare principal components regression and partial least squares regression, and their solution to the problem of multicollinearity. We illustrate the use of both techniques, and demonstrate the superiority of partial least squares.
José Carlos Vega Vilca, Josué Guzman
doaj +1 more source