Results 81 to 90 of about 6,258,593 (311)

Lateral/Basolateral Amygdala Serotonin Type-2 Receptors Modulate Operant Self-administration of a Sweetened Ethanol Solution via Inhibition of Principal Neuron Activity

Frontiers in Integrative Neuroscience, 2014
The lateral/basolateral amygdala (BLA) forms an integral part of the neural circuitry controlling innate anxiety and learned fear. More recently, BLA dependent modulation of self-administration behaviors suggests a much broader role in the regulation of
Brian eMccool, Daniel eChristian, Daniel eChristian, Jonathan eFetzer, Ann eChappell   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Informed Principal and Countervailing Incentives [PDF]

It has been shown by Maskin and Tirole (1990, proposition 11) that with quasi-linear preferences and private values, an informed principal neither gains nor loses if her private information is revealed before contracting takes place.
Pierre Fleckinger
core  

Growth of citrus rootstocks under aluminium stress in hydroponics

Scientia Agricola, 2003
Plants present different degrees of adaptation to aluminium (Al) concentrations in the soil, and the understanding of this characteristic can lead to a viable option for the utilization of acid soils.
Walter Esfrain Pereira, Dalmo Lopes de Siqueira, Mario Puiatti, Carlos Alberto Martínez, Luiz Carlos Chamhum Salomão, Paulo Roberto Cecon   +5 more
doaj  

Elastoplastic Semi-Analytical Solution for Deep Tunnels in Strain-Softening Rock Mass Considering Intermediate Principal Stress and Dilation Behaviour

Applied Sciences
Reliable estimation of squeezing deformation in deep soft-rock tunnels requires an elastoplastic formulation that can capture the post-yield response of the surrounding rock.
Shuyi Xie, Chenghua Shi, Keyue Zheng, Yingming Xiao, Yili Lou, Juan Huang, Guanghui Liu   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Vuillemin’s published papers

, 2018
Il progetto, guidato da Baptiste Mélès (come " junior researcher" del CNRS e )sotto la guida di un'équipe (G. Heinzmann, L. Ménière, B. Mélès) costituita in seno al "Comité Scientifique" degli Archives Jules-Vuillemin (Université de Lorraine ...
M. Buzzoni, G. Heinzmann (principal investigtor), B. Mélès (principal investigtor), L. Ménière (principal investigtor)   +3 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Principal-principal conflicts during crisis

, 2011
This paper explores principal-principal conflicts in corporate governance during times of economic crisis. We address the question: What external and internal governance mechanisms can best protect minority shareholders?
Mike Peng (23429389), Y. Jiang (604133)
core  

ITERATIVE AGGREGATION METHOD FOR SOLVING PRINCIPAL COMPONENT ANALYSIS PROBLEMS

International Journal for Computational Civil and Structural Engineering, 2017
Motivated by the previously developed multilevel aggregation method for solving structural analysis problems a novel two-level aggregation approach for efficient iterative solution of Principal Component Analysis (PCA) problems is proposed.
Vitaly E. Bulgakov
doaj   +1 more source