Results 191 to 200 of about 2,140,628 (292)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Human Retinal Progenitor Cell (hRPC) Migration in Three-Dimensional (3D) Environments of Varying Stiffness and Composition. [PDF]

J Tissue Eng Regen Med
Zhao P, Kundu J, Blanton D, Rezaeeyazdi M, Oudin MJ, Miller MA, Meyer AS, Bencherif SA, Baranov PY, Young MJ, Carrier RL.   +10 more
europepmc   +1 more source

Singular solutions for analytic pseudodifferential operators of principal type

Duke Mathematical Journal, 1980
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optimal Stubble Management Strategies of <i>Caragana tibetica</i> for Enhancing Stress Resistance and Vegetation Restoration. [PDF]

Plants (Basel)
Yuan X, Gao Y, Liang Y.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Determining Olefin Content of Gasoline by Adaptive Partial Least Squares Regression Combined with Near-Infrared Spectroscopy. [PDF]

Molecules
Du B, Yuan H, Hao L, Wu Y, He C, Wang Q, Chen C.   +6 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Higher glass transition temperatures reduce thermal stress cracking in aqueous solutions relevant to cryopreservation. [PDF]

Sci Rep
Kavian S, Sellers R, Sanchez GA, Alvarez C, Aguilar G, Powell-Palm MJ.   +5 more
europepmc   +1 more source

Principal solutions of non-oscillatory self-adjoint linear differential systems [PDF]

Pacific Journal of Mathematics, 1958
openaire   +2 more sources